A differentiated effector T cell repertoire defines a functionally high-risk group of smoldering myeloma patients ...

Antigen-specific B cell profiling uncovers key determinants of SARS-CoV-2 antibody breadth after infection and vaccination. ...

Study design, patient eligibility and treatment This was a phase 1, first-in-human, open-label, nonrandomized, dose-escalation study designed to assess the ...

The Foxp3 transcription factor integrates cell-intrinsic and environmental contexts with epigenetic programs to establish regulatory T cell identity. ...

Freedom of scientific inquiry: reclaiming space for controversy ...

Targeting Treg cells to mitigate inflammation has been a challenge, but a parasite-derived cytokine may be key to engineering a ...

Cell culture Mouse melanoma cell line B16F10 (cat. SCSP-5233), mouse CRC cell line MC38 (cat. SCSP-5431), mouse HCC cell line ...

Foxp3 integrates cell-intrinsic and environmental contexts with epigenetic programs to establish Treg cell molecular identity and function. ...

Citraconate preserves stemness, mitigates ferroptosis, and potentiates T cell antitumor immunity by modulating the PDE1-cAMP-ALOX5 axis. ...

TP2-5 synergizes with multiple antibiotics and attenuates MIC escalation during serial passage We first investigated whether TP2-5 can act as ...