CD300ld on pathologically activated neutrophils promotes tumor immune suppression by binding phosphatidylserine on CD8+ T cells

Mao, Y. et al. The landscape of objective response rate of anti-PD-1/L1 monotherapy across 31 ...

Solid tumors exploit proton-sensing GPR65 for orchestration of an immunosuppressive tumor microenvironment

a 2 × 105 strongly acidic tumor cells (B16F10) were inoculated into the right flank of Gpr65-deficient ...

Activation of CD40 in tumors reprograms the tumor microenvironment

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and ...

Multi-omics profiling reveals tumor microenvironment characteristics linked to immunotherapy response and prognosis in non-small cell lung cancer

Elevated CD8 + T cell infiltration correlates with enhanced immune reactivity The graphic abstract of this study ...

NIH-funded study suggests that testosterone suppresses brain tumor growth in males

Wednesday, May 6, 2026 Findings may warrant exploration of the hormones as glioblastoma treatment In ...

Tumor-localized CD40 agonism with MP0317, a FAP x CD40 DARPin, reprograms the tumor microenvironment in patients with advanced solid tumors: an open-label, nonrandomized, dose-escalation phase 1 study

Study design, patient eligibility and treatment This was a phase 1, first-in-human, open-label, nonrandomized, dose-escalation ...

SLC38A4 promotes Kupffer cell phagocytosis and suppresses tumor liver metastasis

Cell culture Mouse melanoma cell line B16F10 (cat. SCSP-5233), mouse CRC cell line MC38 (cat. ...

Chemokine-defined macrophage niches establish spatial organization of tumor immunity

RecMacs display protumor transcriptional signatures To identify macrophage subsets associated with tumor regression or progression, ...

Macrophages restrict tumor immune infiltration by controlling collagen topography | Science Immunology

In solid tumors, local fibrillar collagen topography is imposed by macrophages and dictates T cell ...

3 Habits You Can Start Today To Increase Your Metabolism

Nutrition is only one piece of the cancer puzzle. Genetics, hormones, lifestyle habits, and environmental ...